Itanapraced

MedChem Express

Itanapraced [749269-83-8]

10

749269-83-8

Research Use Only

99.37

C16H11Cl2FO2

325.16

Itanapraced (CHF5074) is an orally active gamma-secretase modulator and a non-steroidal anti-inflammatory derivative. Itanapraced reduces Abeta42 and Abeta40 secretion with IC 50 values of 3.6 and 18.4 microM, respectively. Itanapraced inhibits cell apoptosis of hippocampal neurons induced by oxygen and glucose deprivation (OGD). Itanapraced can be used for the research of Alzheimers disease [1] [2] .

OC(C1(CC1)C(C=C2)=CC(F)=C2C3=CC=C(Cl)C(Cl)=C3)=O

-20°C,2°C to 8°C

12352200