
Western blot All lanes: ITGB7 antibody at 5.04ug/ml Lane 1: MCF-7 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: A549 whole cell lysate Lane 4: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 87, 72 kDa Observed band size: 87 kDa
ITGB7 Antibody
CSB-PA011891ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetITGB7
Overview
- SupplierCusabio
- Product NameITGB7 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3695
- Target nameITGB7
- Target descriptionintegrin subunit beta 7
- Target synonymsintegrin beta-7, gut homing receptor beta subunit, integrin beta 7 subunit
- HostRabbit
- IsotypeIgG
- Protein IDP26010
- Protein NameIntegrin beta-7
- Scientific DescriptionIntegrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161






