Bio-Connect

ITM2C antibody

Research Use Only
GTX116904
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetITM2C
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    ITM2C antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID81618
  • Target name
    ITM2C
  • Target description
    integral membrane protein 2C
  • Target synonyms
    BRI3; BRICD2C; BRICHOS domain containing 2C; cerebral protein 14; E25; E25C; integral membrane protein 2C; integral membrane protein 3; ITM3; transmembrane protein BRI3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NQX7
  • Protein Name
    Integral membrane protein 2C
  • Scientific Description
    Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Trezise S et al., 2018 Jul 24, Int J Mol Sci
    Read more