Overview
- SupplierGeneTex
- Product NameITM2C antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.7 mg/ml
- IsotypeIgG
- Scientific DescriptionNegative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Trezise S et al., 2018 Jul 24, Int J Mol SciRead more