ITM2C antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX116904
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetITM2C
Overview
- SupplierGeneTex
- Product NameITM2C antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.7 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID81618
- Target nameITM2C
- Target descriptionintegral membrane protein 2C
- Target synonymsBRI3; BRICD2C; BRICHOS domain containing 2C; cerebral protein 14; E25; E25C; integral membrane protein 2C; integral membrane protein 3; ITM3; transmembrane protein BRI3
- HostRabbit
- IsotypeIgG
- Protein IDQ9NQX7
- Protein NameIntegral membrane protein 2C
- Scientific DescriptionNegative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Trezise S et al., 2018 Jul 24, Int J Mol SciRead more