Ivacaftor

MedChem Express

Ivacaftor [873054-44-5]

10

873054-44-5

Research Use Only

99.90

C24H28N2O3

392.49

Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively.

CC(C)(C1=C(C=C(C(C(C)(C)C)=C1)O)NC(C2=CNC3=C(C2=O)C=CC=C3)=O)C

-20°C,2°C to 8°C

12352200