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Ivarmacitinib

M28457
AbMole BioScience
CAS Number1445987-21-2
Product group Chemicals
Molecular Weight414.48
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Ivarmacitinib
  • Delivery Days Customer
    9
  • CAS Number
    1445987-21-2
  • Certification
    Research Use Only
  • Molecular Formula
    C18H22N8O2S
  • Molecular Weight
    414.48
  • Scientific Description
    Ivarmacitinib (SHR0302) is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects.
  • UNSPSC
    12352200

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