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IWP-3

HY-100536
MedChem Express
CAS Number687561-60-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.27
Molecular Weight484.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IWP-3 [687561-60-0]
  • Delivery Days Customer
    10
  • CAS Number
    687561-60-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.27
  • Molecular Formula
    C22H17FN4O2S3
  • Molecular Weight
    484.59
  • Scientific Description
    IWP-3 is an potent inhibitor of Wnt production with an IC 50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1gamma3 and CK1epsilon only moderately and does not inhibit CK1alpha [1] [2] .
  • SMILES
    O=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=C(F)C=C5)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200