IXA4

AbMole BioScience

IXA4

9

1185329-96-7

Chemical

Research Use Only

C24H28N4O4

436.5

IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation.

CN(CCOC1=CC=C(C)C=C1)C(=O)C[N]2C=C(NC(=O)CCOC3=CC=CC=C3)C=N2

12352200