Ixazomib citrate

MedChem Express

Ixazomib citrate [1239908-20-3]

10

1239908-20-3

Research Use Only

99.89

C20H23BCl2N2O9

517.12

Ixazomib citrate (MLN9708) is a reversible inhibitor of the chymotrypsin-like proteolytic beta5 site of the 20S proteasome with an IC 50 of 3.4 nM and a K i of 0.93 nM.

O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O

-20°C,2°C to 8°C

12352200