Bio-Connect

J-1048 [2374772-60-6]

HY-149403
MedChem Express
CAS Number2374772-60-6
Product group Chemicals
Molecular Weight460.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    J-1048 [2374772-60-6]
  • Delivery Days Customer
    14
  • CAS Number
    2374772-60-6
  • Certification
    Research Use Only
  • Molecular Formula
    C23H17FN6S2
  • Molecular Weight
    460.55
  • Scientific Description
    J-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-beta/Smad signaling pathway[1].
  • SMILES
    FC1=CC(NC(CN2C=C(C3=CC4=NSN=C4C=C3)C(C5=CC=CC(C)=N5)=N2)=S)=CC=C1
  • UNSPSC
    12131703