J-1048 [2374772-60-6]
HY-149403
CAS Number2374772-60-6
Product group Chemicals
Molecular Weight460.55
Overview
- SupplierMedChem Express
- Product NameJ-1048 [2374772-60-6]
- Delivery Days Customer14
- CAS Number2374772-60-6
- CertificationResearch Use Only
- Molecular FormulaC23H17FN6S2
- Molecular Weight460.55
- Scientific DescriptionJ-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-beta/Smad signaling pathway[1].
- SMILESFC1=CC(NC(CN2C=C(C3=CC4=NSN=C4C=C3)C(C5=CC=CC(C)=N5)=N2)=S)=CC=C1
- UNSPSC12131703