J-1063 [2374772-46-8]
HY-145855
CAS Number2374772-46-8
Product group Chemicals
Molecular Weight425.51
Overview
- SupplierMedChem Express
- Product NameJ-1063 [2374772-46-8]
- Delivery Days Customer10
- CAS Number2374772-46-8
- CertificationResearch Use Only
- Molecular FormulaC24H19N5OS
- Molecular Weight425.51
- Scientific DescriptionJ-1063 is a potent, selective and orally active ALK5 inhibitor with an IC50 of 0.039 microM. J-1063 shows anti-fibrotic effect by the inhibition of inflammatory infiltration, collagen deposition, and hepatocytes necrosis. J-1063 has the potential for the research of liver fibrosis[1].
- SMILESCC1=NC(C2=NN(C=C2C3=CC4=C(S3)C=CN=C4)CC(NC5=CC=CC=C5)=O)=CC=C1
- UNSPSC12131703