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(+/-)-J-113397

HY-107721
MedChem Express
CAS Number217461-40-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.59
Molecular Weight399.57
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (+/-)-J-113397 [217461-40-0]
  • Delivery Days Customer
    10
  • CAS Number
    217461-40-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.59
  • Molecular Formula
    C24H37N3O2
  • Molecular Weight
    399.57
  • Scientific Description
    (+/-)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist with a K i of 1.8 nM for cloned human ORL1. J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPgammaS binding to CHO cells expressing ORL1 with an IC 50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1] .
  • SMILES
    O=C1N([C@](CCN2CC3CCCCCCC3)([H])[C@H](C2)CO)C4=CC=CC=C4N1CC
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200