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ProductsBack/J30-8 [2366255-71-0]
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CgoaEGY7PYeETWubAAAAAGfPNtU170.png
CgoaEGY7PYeETWubAAAAAGfPNtU170.png

J30-8 [2366255-71-0]

Research Use Only
T11702
TargetMol Chemicals
CAS Number2366255-71-0
DownloadMSDS
Product group Chemicals
Molecular Weight373.79
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    J30-8 [2366255-71-0]
  • Delivery Days Customer
    14
  • CAS Number
    2366255-71-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    J30-8
  • Molecular Formula
    C17H9ClFN3O2S
  • Molecular Weight
    373.79
  • Scientific Description
    J30-8 is a subtype-selective and potent JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity for the study of neurodegenerative diseases such as Alzheimers disease.
  • Shelf life instruction
    3 years
  • SMILES
    Fc1ccc2NC(=O)\C(=C3/S\C(NC3=O)=N/c3ccccc3Cl)c2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Dou X, et al. Multistage Screening Reveals 3-Substituted Indolin-2-one Derivatives as Novel and Isoform-Selective c-Jun N-terminal Kinase 3 (JNK3) Inhibitors: Implications to Drug Discovery for Potential Treatment of Neurodegenerative Diseases. J Med Chem. 2019 Jul 25;62(14):6645-6664.
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