Induction of IL-6 expression in human dermal fibroblasts by Jagged-1 (human):Fc (human) (rec.) (Prod. No. AG-40A-0081). Method: Jagged-1 (human):Fc was coated on a 12-well plate at 1microg/ml overnight at 4°C. Human dermal fibroblasts were cultured in
Induction of IL-6 expression in human dermal fibroblasts by Jagged-1 (human):Fc (human) (rec.) (Prod. No. AG-40A-0081). Method: Jagged-1 (human):Fc was coated on a 12-well plate at 1microg/ml overnight at 4°C. Human dermal fibroblasts were cultured in
Jagged-1 (human):Fc (human) (rec.)
AG-40A-0081
Overview
- SupplierAdipoGen Life Sciences
- Product NameJagged-1 (human):Fc (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration0.5 mg/ml
- Estimated Purity>90%
- FormulationLiquid
- Protein IDP78504
- Protein NameProtein jagged-1
- Scientific DescriptionJagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF). - Protein. Signal peptide and extracellular domain of human Jagged-1 (HJ1; CD339) (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm-filtered solution in PBS. Purity: >90% (SDS-PAGE). Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202
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