Bio-Connect

JAK3-IN-17

HY-173601
MedChem Express
Molecular Weight358.37
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JAK3-IN-17
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C21H15FN4O
  • Molecular Weight
    358.37
  • Scientific Description
    JAK3-IN-17 (Compound X15) is an orally active JAK3 inhibitor (IC50: 14.56 nM). JAK3-IN-17 inhibits the production of IL-2 and IL-6 in a DNCB-induced mouse atopic dermatitis model and exhibits anti-inflammatory activity[1].
  • SMILES
    O=C(C=C)NC1=CC=CC(C2=CN=C3C=CC(C4=C(F)N=CC=C4)=CN32)=C1
  • UNSPSC
    12352200