JAK3/BTK-IN-6 [2243136-03-8]

MedChem Express

JAK3/BTK-IN-6 [2243136-03-8]

10

2243136-03-8

Research Use Only

C21H17BF3N5O3

455.20

JAK3/BTK-IN-6 (compound 14h) is a potent BTK and JAK3 dual inhibitor, with IC50 values of 0.6 and 0.4 nM, respectively. JAK3/BTK-IN-6 shows good metabolic stability in human liver microsome. JAK3/BTK-IN-6 can be used for hematological and immune diseases research[1].

C=CC(NC1=CC(NC2=C(C=NC(NC3=CC=C4B(OCC4=C3)O)=N2)C(F)(F)F)=CC=C1)=O

12131703