Jasplakinolide

MedChem Express

Jasplakinolide [102396-24-7]

9

102396-24-7

Research Use Only

99.50

C36H45BrN4O6

709.67

Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a K d of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge , has both fungicidal and anti-cancer activity [1] [2] .

BrC1=C(C2=CC=CC=C2N1)C[C@@H](N(C([C@@H](NC([C@H](C/C(C)=C/[C@@H]3C)C)=O)C)=O)C)C(N[C@](C(C=C4)=CC=C4O)([H])CC(O[C@H](C3)C)=O)=O

-20°C,-80°C

12352200