Jatrorrhizine (chloride)

MedChem Express

Jatrorrhizine (chloride) [6681-15-8]

5

6681-15-8

Research Use Only

99.88

C20H20ClNO4

373.83

Jatrorrhizine chloride is an alkaloid isolated from? Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities [1] . Jatrorrhizine chloride is a potent and orally active inhibitor of? AChE ?( IC 50 =872 nM) over >115-fold selectivity for BuChE [2] . Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters [3] .

COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1.[Cl-]

2°C to 8°C

12352200