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ProductsBack/Jatrorrhizine (chloride) [6681-15-8]

Jatrorrhizine (chloride) [6681-15-8]

HY-N0740
MedChem Express
CAS Number6681-15-8
Product group Chemicals
Estimated Purity99.82
Molecular Weight373.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Jatrorrhizine (chloride) [6681-15-8]
  • Delivery Days Customer
    5
  • CAS Number
    6681-15-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.82
  • Molecular Formula
    C20H20ClNO4
  • Molecular Weight
    373.83
  • Scientific Description
    Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities[1]. Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE[2]. Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters[3].
  • SMILES
    COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1.[Cl-]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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