JB062 [2417988-00-0]

MedChem Express

JB062 [2417988-00-0]

10

2417988-00-0

Research Use Only

C19H17NO4

323.34

JB062 is a nonmuscle myosin inhibitor with IC50 values of 1.6, 5.4, and >100 microM for Skeletal muscle myosin, Cardiac muscle myosin, and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].

OC(C1=CC=CC=C1O2)=C(/C(C)=N/CC3=CC=C(OC)C=C3)C2=O

-20°C,2°C to 8°C

12131703