JBS Bright Red [548-24-3]

Jena Bioscience

JBS Bright Red [548-24-3]

5

548-24-3

Research Use Only

C20H6Br2N2Na2O9

624.08 g/mol

Crystallization screening with high concentrations of precipitant and salt may lead to the formation of salt crystals. It is quite difficult to make a distinction between these false positives and true protein crystals. Staining of crystals with appropriate dyes is a very straightforward method to differentiate between macromolecular crystals and salt crystals [1]. Protein and salt crystals differ substantially in their solvent content. Small crystal dyes, like JBS Bright Red, are able to permeate the solvent channels of a protein, thus coloring the protein red. In contrast, salt crystals are tightly packed and do not possess large solvent channels. They will therefore remain colourless.

c1(c(cc2c(c1Br)Oc1c(C32c2ccccc2C(=O)O3)cc(c(c1Br)[O-])[N+](=O)[O-])[N+](=O)[O-])[O-].[Na].[Na]

RT

12352200