JBS True Blue [61-73-4]

Jena Bioscience

JBS True Blue [61-73-4]

5

61-73-4

Research Use Only

C16H18ClN3S * H2O

319.85 g/mol (anhydrous)

Crystallization screening with high concentrations of precipitant and salt may lead to the formation of salt crystals. It is quite difficult to make a distinction between these false positives and true protein crystals. Staining of crystals with appropriate dyes is a very straightforward method to differentiate between macromolecular crystals and salt crystals [1]. Protein and salt crystals differ substantially in their solvent content. Small crystal dyes, like JBS True Blue, are able to permeate the solvent channels of a protein, thus coloring the protein blue. In contrast, salt crystals are tightly packed and do not possess large solvent channels. They will therefore remain colourless.

[Cl-].s1c2c(nc3c1cc(N(C)C)cc3)ccc(=[N+](C)C)c2

RT

12352200