Bio-Connect

JBSNF-000088 [7150-23-4]

HY-112584
MedChem Express
CAS Number7150-23-4
Product group Chemicals
Estimated Purity99.94
Molecular Weight152.15
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JBSNF-000088 [7150-23-4]
  • Delivery Days Customer
    10
  • CAS Number
    7150-23-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C7H8N2O2
  • Molecular Weight
    152.15
  • Scientific Description
    JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 microM, 2.8 microM, and 5.0 microM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease[1].
  • SMILES
    O=C(N)C1=CC=C(OC)N=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200