JC-171 [2112809-98-8]

MedChem Express

JC-171 [2112809-98-8]

9

2112809-98-8

Research Use Only

98.41

C16H17ClN2O5S

384.83

JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 microM for inhibiting LPS/ATP-induced interleukin-1beta (IL-1beta) release from J774A.1 macrophages[1].

O=C(NCCC1=CC=C(S(=O)(NO)=O)C=C1)C2=CC(Cl)=CC=C2OC

-20°C,2°C to 8°C

12352200