JG-98 [1456551-16-8]

MedChem Express

JG-98 [1456551-16-8]

5

1456551-16-8

Research Use Only

99.88

C24H21Cl2N3OS3

534.54

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages[1][2][3].

CN1/C(SC2=CC(Cl)=CC=C12)=C3S/C(N(CC)C\3=O)=C\C4=[N+](C=CS4)CC5=CC=CC=C5.[Cl-]

2°C to 8°C

12352200