JG26 [1464910-32-4]
HY-120852
CAS Number1464910-32-4
Product group Chemicals
Estimated Purity98.14
Molecular Weight594.27
Overview
- SupplierMedChem Express
- Product NameJG26 [1464910-32-4]
- Delivery Days Customer10
- CAS Number1464910-32-4
- CertificationResearch Use Only
- Estimated Purity98.14
- Molecular FormulaC19H22Br2N4O6S
- Molecular Weight594.27
- Scientific DescriptionJG26 is an ADAM inhibitor with IC50 values of 12 nM, 1.9 nM, and 150 nM for ADAM8, ADAM17, and ADAM10, respectively. JG26 inhibits MMP-12 with an IC50 value of 9.4 nM. JG26 inhibits AngII (HY-13948)-induced EGFR transactivation and ERK activation. JG26 increases the expression of ACE2, inhibits the cleavage of CD23, reduces the infection of SARS-CoV-2. JG26 inhibits colorectal cancer metastasis. JG26 can be used for research on Hodgkin lymphoma and vascular diseases[1][2][3][4][5][6].
- SMILESO=C([C@@H](CCCNC(N)=O)NS(=O)(C1=CC=C(C=C1)OCC2=CC(Br)=CC(Br)=C2)=O)NO
- Storage Instruction2°C to 8°C
- UNSPSC12352200