JGB1741 [1256375-38-8]
HY-111329
CAS Number1256375-38-8
Product group Chemicals
Estimated Purity99.37
Molecular Weight440.56
Overview
- SupplierMedChem Express
- Product NameJGB1741 [1256375-38-8]
- Delivery Days Customer10
- CAS Number1256375-38-8
- CertificationResearch Use Only
- Estimated Purity99.37
- Molecular FormulaC27H24N2O2S
- Molecular Weight440.56
- Scientific DescriptionJGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ~15 microM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 microM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research[1].
- SMILESOC1=C(C2=C(C=C1)C=CC=C2)/C=N/C3=C(C4=C(S3)CCCC4)C(NCC5=CC=CC=C5)=O
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
Related products
Product group Chemicals
JGB1741ORB1306098
CAS Number1256375-38-8
Estimated Purity97.24%
Molecular Weight440.56
- SizePrice
![JGB1741 [1256375-38-8] [1256375-38-8]](https://www.targetmol.com/group3/M00/35/FD/CgoaEWayM9WEEA0eAAAAAG9_Tow018.png)
Product group Chemicals
References
CAS Number1256375-38-8
Estimated Purity≥95%
Molecular Weight440.56
- SizePrice