JH-VIII-157-02

MedChem Express

JH-VIII-157-02 [1639422-97-1]

10

1639422-97-1

Research Use Only

98.98

C28H27N5O2

465.55

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1

-20°C,2°C to 8°C

12352200