JI051 [2234281-75-3]

MedChem Express

JI051 [2234281-75-3]

5

2234281-75-3

Research Use Only

98.0

C22H24N2O3

364.44

JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].

O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC

-20°C,2°C to 8°C

12352200