Bio-Connect

JMI-105 [2227315-30-0]

HY-147849
MedChem Express
CAS Number2227315-30-0
Product group Chemicals
Molecular Weight337.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JMI-105 [2227315-30-0]
  • Delivery Days Customer
    10
  • CAS Number
    2227315-30-0
  • Certification
    Research Use Only
  • Molecular Formula
    C20H23N3O2
  • Molecular Weight
    337.42
  • Scientific Description
    JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQS (3D7; IC50=8.8 microM) and CQR (RKL-9; IC50=14.3 microM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent[1].
  • SMILES
    CC(C1=CC=C(C)C(OCC2=CN(C3=CC=C(OC)C=C3)N=N2)=C1)C
  • UNSPSC
    12131703