JMI-105 [2227315-30-0]
HY-147849
Overview
- SupplierMedChem Express
- Product NameJMI-105 [2227315-30-0]
- Delivery Days Customer10
- CAS Number2227315-30-0
- CertificationResearch Use Only
- Molecular FormulaC20H23N3O2
- Molecular Weight337.42
- Scientific DescriptionJMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQS (3D7; IC50=8.8 microM) and CQR (RKL-9; IC50=14.3 microM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent[1].
- SMILESCC(C1=CC=C(C)C(OCC2=CN(C3=CC=C(OC)C=C3)N=N2)=C1)C
- UNSPSC12131703