Bio-Connect

JMS-053 [1954650-11-3]

HY-135457
MedChem Express
CAS Number1954650-11-3
Product group Chemicals
Estimated Purity98.0
Molecular Weight256.28
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JMS-053 [1954650-11-3]
  • Delivery Days Customer
    10
  • CAS Number
    1954650-11-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C13H8N2O2S
  • Molecular Weight
    256.28
  • Scientific Description
    JMS-053 is a potent, selective and reversible PTP4A inhibitor, with IC50s of 29.1 nM, 48.0 nM, 34.7 nM, 92.6 nM, and 207.6 nM for PTP4A1, PTP4A2, PTP4A3, CDC25B, and DUSP3, respectively. JMS-053 can inhibit cancer cell migration and spheroid growth in vitro, attenuate in vivo ovarian tumor growth[1].
  • SMILES
    O=C1C(C=C(C2=CC=CC=C2)S3)=C3C(C(N1)=O)=N
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200