JMV 390-1

MedChem Express

JMV 390-1 [148473-36-3]

10

148473-36-3

Research Use Only

C23H35N3O6

449.54

JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC 50 values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium [1] .

O=C(N[C@H](C(O)=O)CC(C)C)[C@H]([C@@H](C)CC)NC([C@@H](CC(NO)=O)CC1=CC=CC=C1)=O

12352200