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JND3229

HY-119944
MedChem Express
CAS Number2260886-64-2
Product group Chemicals
Estimated Purity99.78
Molecular Weight617.18
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JND3229 [2260886-64-2]
  • Delivery Days Customer
    9
  • CAS Number
    2260886-64-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.78
  • Molecular Formula
    C33H41ClN8O2
  • Molecular Weight
    617.18
  • Scientific Description
    JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma[1].
  • SMILES
    CC1=CC(NC2=NC(N([C@@H]3CC[C@@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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