JND3229
HY-119944
CAS Number2260886-64-2
Product group Chemicals
Estimated Purity99.78
Molecular Weight617.18
Overview
- SupplierMedChem Express
- Product NameJND3229 [2260886-64-2]
- Delivery Days Customer9
- CAS Number2260886-64-2
- CertificationResearch Use Only
- Estimated Purity99.78
- Molecular FormulaC33H41ClN8O2
- Molecular Weight617.18
- Scientific DescriptionJND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma[1].
- SMILESCC1=CC(NC2=NC(N([C@@H]3CC[C@@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200