JNJ-10397049

MedChem Express

JNJ-10397049 [708275-58-5]

10

708275-58-5

Research Use Only

99.91

C19H20Br2N2O3

484.18

JNJ-10397049 is a potent and selective orexin 2 receptor (OX 2 R) antagonist, with a pK i of 8.3. JNJ-10397049 is 600-fold selective for the OX 2 R over the OX 1 R [1] [2] .

BrC1=C(NC(N[C@@H]2[C@H](C3=CC=CC=C3)OC(C)(C)OC2)=O)C=CC(Br)=C1

-20°C,2°C to 8°C

12352200