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JNJ-16241199

HY-10226
MedChem Express
CAS Number604769-01-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.05
Molecular Weight413.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-16241199 [604769-01-9]
  • Delivery Days Customer
    5
  • CAS Number
    604769-01-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.05
  • Molecular Formula
    C19H19N5O4S
  • Molecular Weight
    413.45
  • Scientific Description
    JNJ-16241199 (R306465) is an orally active, selectivehydroxamate-based histone deacetylase (HDAC) inhibitor, with theIC50of 3.3 nM and 23 nM for HDAC1and HDAC8, respectively.JNJ-16241199induces histone 3 acetylation and strongly increases the expression of p21waf1, cip1 in A2780 ovarian carcinoma cells.JNJ-16241199 inducescell apoptosisand shows anticancer activityin a broad spectrum of human malignancies. JNJ-16241199 can be used for cancer study[1].
  • SMILES
    O=S(N(CC1)CCN1C2=NC=C(C(NO)=O)C=N2)(C3=CC=C4C(C=CC=C4)=C3)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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