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ProductsBack/JNJ-28312141 [885692-52-4]

JNJ-28312141 [885692-52-4]

HY-13496

CAS Number885692-52-4

Product group Chemicals

Molecular Weight460.57

Overview

Supplier
MedChem Express
Product Name
JNJ-28312141 [885692-52-4]
Delivery Days Customer
102
CAS Number
885692-52-4
Certification
Research Use Only
Hazard Information
h302-h315-h319-h335,p261-p264-p270-p271-p280-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501
Molecular Formula
C26H32N6O2
Molecular Weight
460.57
Scientific Description
JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model[1].
SMILES
O=C(C1=NC(C#N)=CN1)NC2=C(C3=CCCCC3)C=C(C4CCN(C(CN(C)C)=O)CC4)C=C2
UNSPSC
12352200

MSDS

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