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JNJ-40418677 [1146594-87-7]

JNJ-40418677 [1146594-87-7]

T24210
TargetMol Chemicals
CAS Number1146594-87-7
DownloadMSDS
Product group Chemicals
Molecular Weight480.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JNJ-40418677 [1146594-87-7]
  • Delivery Days Customer
    44
  • CAS Number
    1146594-87-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JNJ-40418677
  • Molecular Formula
    C26H22F6O2
  • Molecular Weight
    480.44
  • Scientific Description
    JNJ-40418677 is a gamma-secretase modulator that selectively blocks gamma-site cleavage of the APP without affecting the processing of Notch.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)C[C@H](C(O)=O)c1cc(cc(c1)-c1ccc(cc1)C(F)(F)F)-c1ccc(cc1)C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Chronic treatment with a novel gamma-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimers disease. Van Broeck B et al., 2011 May, Br J Pharmacol
    Read more

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