JNJ-42165279 [1346528-50-4]

TargetMol Chemicals

JNJ-42165279 [1346528-50-4]

4

1346528-50-4

Chemical

Research Use Only

JNJ-42165279

99.89%

C18H17ClF2N4O3

410.8

JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 microM) exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels, at which concentration it does not produce >50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 (10 microM) also does not inhibit CYPs (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG.

3 years

FC1(F)Oc2ccc(CN3CCN(CC3)C(=O)Nc3cnccc3Cl)cc2O1

-20°C

12352200