Bio-Connect

JNJ-46281222

HY-120530
MedChem Express
CAS Number1254980-38-5
Product group Chemicals
Estimated Purity98.77
Molecular Weight414.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-46281222 [1254980-38-5]
  • Delivery Days Customer
    5
  • CAS Number
    1254980-38-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.77
  • Molecular Formula
    C23H25F3N4
  • Molecular Weight
    414.47
  • Scientific Description
    JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator) with nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71)[1].
  • SMILES
    FC(C1=C(CN2CCC(C3=CC=CC=C3)CC2)C=CN4C1=NN=C4CC5CC5)(F)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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