JNJ-55511118 [2036081-86-2]

MedChem Express

JNJ-55511118 [2036081-86-2]

10

2036081-86-2

Research Use Only

98.9

C14H8ClF3N2O2

328.67

JNJ-55511118 is a highly potent, reversible, and selective AMPA receptor inhibitor selective for TARP-gamma8. JNJ-55511118 fully displaces the radioligand (20 nM) with the Ki of 26 nM in competition binding experiments. JNJ-55511118 is a tool molecule with potential therapeutic utility as an anticonvulsant or neuroprotectant[1].

O=C1NC2=C(N1)C=C(C3=C(OC(F)(F)F)C=CC=C3Cl)C=C2

-20°C,2°C to 8°C

12352200