Bio-Connect

JNJ-7777120

HY-13508
MedChem Express
CAS Number459168-41-3
Product group Chemicals
Estimated Purity99.96
Molecular Weight277.75
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-7777120 [459168-41-3]
  • Delivery Days Customer
    10
  • CAS Number
    459168-41-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.96
  • Molecular Formula
    C14H16ClN3O
  • Molecular Weight
    277.75
  • Scientific Description
    JNJ-7777120 is a potent and selective histamine H 4 receptor antagonist ( K i =4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory [1] [2] .
  • SMILES
    O=C(C(N1)=CC2=C1C=CC(Cl)=C2)N3CCN(C)CC3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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