Bio-Connect

JNK-1-IN-3

ORB2665400
Biorbyt
Estimated Purity98.00%
Product group Chemicals
Molecular Weight368.36
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Overview

  • Supplier
    Biorbyt
  • Product Name
    JNK-1-IN-3
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C19H17FN4O3
  • Molecular Weight
    368.36
  • Scientific Description
    JNK-1-IN-3 (Compound 9e) acts as a JNK1 inhibitor, both reducing JNK1 gene expression and lowering the protein levels of its phosphorylated form. It concurrently diminishes the expression of downstream targets c-Jun and c-Fos in tumors, while also restoring p53 activity. Exhibiting broad-spectrum antiproliferative effects, JNK-1-IN-3 is particularly effective against renal and breast cancer cell lines, showing significant anticancer activity both in vivo and in vitro.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200