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JNK2 antibody [N1C3]

Research Use Only
GTX105523
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Insect, Mouse, Rat
TargetMAPK9
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    JNK2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody may cross with JNK1 or JNK3.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.57 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5601
  • Target name
    MAPK9
  • Target description
    mitogen-activated protein kinase 9
  • Target synonyms
    c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; Jun kinase; MAP kinase 9; MAPK 9; mitogen-activated protein kinase 9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a; stress-activated protein kinase 1a; stress-activated protein kinase JNK2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this genes mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
  • Reactivity
    Human, Insect, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Protein Phosphatase 2A in Lipopolysaccharide-Induced Cyclooxygenase-2 Expression in Murine Lymphatic Endothelial Cells. Chuang YF et al., 2015, PLoS One
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  • Characterization of an insecticidal toxin and pathogenicity of Pseudomonas taiwanensis against insects. Chen WJ et al., 2014 Aug, PLoS Pathog
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