Bio-Connect

JPS016 TFA

T77938
TargetMol Chemicals
Molecular Weight1012.14
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JPS016 TFA
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JPS016 TFA
  • Molecular Formula
    C50H64F3N7O10S
  • Molecular Weight
    1012.14
  • Scientific Description
    JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a substantial increase in differentially expressed genes and augmented apoptosis in HCT116 cells [1].
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200