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JPT1 Polyclonal Antibody

RD218906A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetJPT1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    JPT1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.6 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID51155
  • Target name
    JPT1
  • Target description
    Jupiter microtubule associated homolog 1
  • Target synonyms
    androgen-regulated protein 2; ARM2; hematological and neurological expressed 1 protein; HN1; HN1A; jupiter microtubule associated homolog 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 Ser-33 phosphorylation and degradation through the suppression of the inhibitory Ser-9 phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203