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JQ-1 carboxylic acid

M6096
AbMole BioScience
CAS Number202592-23-2
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9804
Molecular Weight400.88
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    JQ-1 carboxylic acid
  • Delivery Days Customer
    9
  • CAS Number
    202592-23-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9804
  • Molecular Formula
    C19H17ClN4O2S
  • Molecular Weight
    400.88
  • Scientific Description
    (+)-JQ1 carboxylic acid, the carboxylic acid form of (+)-JQ1, is a potent BET bromodomain inhibitor for downregulating PD-L1 expression on the surface of tumor cells. JQ-1 carboxylic acid can be used as a precursor to synthesize PROTACs, which targets BET bromodomains.
  • SMILES
    CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(O)=O)N=C2C4=CC=C(Cl)C=C4)C
  • UNSPSC
    12352200