JQEZ5

MedChem Express

JQEZ5 [1913252-04-6]

9

1913252-04-6

98.08

C30H38N8O2

542.68

JQEZ5 is a potent and selective EZH2 lysine methyltransferase inhibitor. JQEZ5 SAM-competitively inhibits polycomb repressive complex 2 (PRC2) with an IC 50 of 80 nM. JQEZ5 has anti-tumor effects [1] .

CC(N1N=CC2=C(C(NCC3=C(C=C(NC3=O)C)CCC)=O)C=C(C4=CC=C(N=C4)N5CCN(C)CC5)N=C12)C

-20°C,2°C to 8°C

12352200