JTE-607 Dihydrochloride
E0314
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameJTE-607 Dihydrochloride [188791-09-5]
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionJTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis. JTE-607 is a multiple cytokine production inhibitor that targets CPSF3 and inhibits pre-mRNA processing. JTE-607 inhibits tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50 values of 11 nM, 5.9 nM, 8.8 nM, 7.3 nM and 9.1 nM, respectively.
- UNSPSC12352200