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JW67

HY-108442
MedChem Express
CAS Number442644-28-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.15
Molecular Weight394.38
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JW67 [442644-28-2]
  • Delivery Days Customer
    10
  • CAS Number
    442644-28-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.15
  • Molecular Formula
    C21H18N2O6
  • Molecular Weight
    394.38
  • Scientific Description
    JW67 inhibits the canonical Wnt signaling with an IC 50 of 1.17microM [1] . JW67 affects the multiprotein complex consisting of beta-catenin/GSK-3beta/AXIN/APC/CK1 that rapidly reduces active beta-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth [1] .
  • SMILES
    O=C1C2(OCC3(COC4(C5=CC=CC=C5NC4=O)OC3)CO2)C6=CC=CC=C6N1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200