JX06

MedChem Express

JX06 [729-46-4]

10

729-46-4

Research Use Only

99.78

C10H16N2O2S4

324.51

JX06 is a potent, selective and covalent inhibitor of PDK . JX06 inhibits PDK1 , PDK2 and PDK3 with IC 50 s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity [1] .

S=C(N1CCOCC1)SSC(N2CCOCC2)=S

-20°C

12352200