K00546 [443798-47-8]

MedChem Express

K00546 [443798-47-8]

9

443798-47-8

Research Use Only

98.08

C15H13F2N7O2S2

425.44

K00546 is a potent CDK1 and CDK2 inhibitor with IC50s of 0.6 nM and 0.5 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. K00546 is also a potent CDC2-like kinase 1 (CLK1) and CLK3 inhibitor with IC50s of 8.9 nM and 29.2 nM, respectively[1][2][3].

S=C(N1N=C(NC2=CC=C(S(=O)(N)=O)C=C2)N=C1N)NC3=C(F)C=CC=C3F

-20°C,2°C to 8°C

12352200