K145 (hydrochloride)

MedChem Express

K145 (hydrochloride) [1449240-68-9]

5

1449240-68-9

Research Use Only

99.63

C18H25ClN2O3S

384.92

K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 microM and a Ki of 6.4 microM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity[1].

O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl

2°C to 8°C

12352200